Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.44 |
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759815 | 0.78 | MAOA (0.44) | MAOAMAOBMTNR1AMTNR1B | |
| SCHEMBL1930695 | 0.78 | MAOA (0.63) | MAOAMAOBGAA | |
| SCHEMBL4566671 | 0.71 | MAOA (0.44) | MAOAMAOB | |
| SCHEMBL24044182 | 0.69 | DEGS1 (0.41) | MAOAMAOBMTNR1AMTNR1BGAA | |
| SCHEMBL30680 | 0.68 | MAOA (0.48) | MAOAMAOB | |
| SCHEMBL7767040 | 0.68 | MAOA (0.54) | MAOAMAOB | |
| SCHEMBL1256493 | 0.67 | MAOA (0.48) | MAOAMAOB | |
| SCHEMBL21568847 | 0.67 | RECQL (0.47) | MTNR1AMTNR1B | |
| SCHEMBL19983213 | 0.67 | MAOA (0.59) | MAOAMAOBMTNR1AMTNR1BGAA | |
| SCHEMBL3031432 | 0.67 | MAOA (0.44) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2943483-B1 | BENZYLAMINE DERIVATIVES | KALVISTA PHARMACEUTICALS LTD (GB) | 2017-03-01 | — | — | EP | disclosed |