SCHEMBL18570879

SCHEMBL18570879

NC(C=O)Cc1ccc(CCCCC2OCCO2)cc1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.34
ENPP2 Q13822 2/20 0.34
FDFT1 P37268 1/20 0.33
SPHK2 Q9NRA0 4/20 0.33
SPHK1 Q9NYA1 3/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20275323 0.90 ALOX5 (0.32)
SCHEMBL18571376 0.81 SLC7A5 (0.31)
SCHEMBL826532 0.81 SLC7A5 (0.50)
SCHEMBL14679505 0.76 ANPEP (0.38)
SCHEMBL826498 0.76 SLC7A5 (0.51)
SCHEMBL14679511 0.73 ANPEP (0.35) THRATHRB
SCHEMBL826925 0.70 SLC7A5 (0.54)
SCHEMBL7020219 0.69 ESR1 (0.48)
SCHEMBL1013285 0.68 TAAR1 (0.55)
SCHEMBL1013284 0.68 TAAR1 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3336103-B1 ANTIBODIES COMPRISING MULTIPLE SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE SUTRO BIOPHARMA INC (US) 2021-03-17 EP disclosed
EP-3135690-A1 MODIFIED FC PROTEINS COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES OF THE SAME, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE Sutro Biopharma, Inc. (US) 2017-03-01 EP disclosed