Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 13/20 | 0.38 |
| ▸ | CTSL | P07711 | 9/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185393 | 0.83 | CNR2 (0.42) | CNR2CNR1 | |
| SCHEMBL186629 | 0.80 | HTR2A (0.39) | CNR2CNR1 | |
| Trifluoroacetic Acid SCHEMBL14856625 | 0.80 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL185747 | 0.79 | CNR2 (0.39) | CNR2CNR1 | |
| SCHEMBL2809946 | 0.79 | CNR2 (0.39) | CNR2 | |
| SCHEMBL185320 | 0.79 | GAA (0.36) | CNR2CNR1 | |
| SCHEMBL13128856 | 0.78 | CNR2 (0.36) | CTSLCNR2 | |
| SCHEMBL185884 | 0.78 | CNR2 (0.38) | CNR2CNR1 | |
| SCHEMBL2805697 | 0.76 | RAB9A (0.41) | CNR2 | |
| SCHEMBL2807298 | 0.76 | CNR2 (0.40) | CTSLCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |
| EP-2401256-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097372-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |