Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.49 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.47 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 10/20 | 0.46 |
| ▸ | ACE | P12821 | 8/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21572784 | 1.00 | GPR88 (0.49) | GPR88SRRPSAT1MMEACE | |
| SCHEMBL1908566 | 1.00 | GPR88 (0.49) | GPR88SRRPSAT1MMEACE | |
| SCHEMBL18059572 | 1.00 | GPR88 (0.49) | GPR88SRRPSAT1MMEACE | |
| SCHEMBL18059571 | 1.00 | GPR88 (0.49) | GPR88SRRPSAT1MMEACE | |
| SCHEMBL609953 | 1.00 | GPR88 (0.49) | GPR88SRRPSAT1MMEACE | |
| SCHEMBL597164 | 1.00 | GPR88 (0.49) | GPR88SRRPSAT1MMEACE | |
| SCHEMBL24404055 | 1.00 | GPR88 (0.49) | GPR88SRRPSAT1MMEACE | |
| SCHEMBL598890 | 1.00 | GPR88 (0.49) | GPR88SRRPSAT1MMEACE | |
| Hydrochloric Acid SCHEMBL597844 | 0.99 | GPR88 (0.48) | GPR88SRRPSAT1MMEACE | |
| SCHEMBL7426879 | 0.99 | GPR88 (0.48) | GPR88SRRPSAT1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017033212-A1 | PREPARATION OF SACUBITRIL AND SALT THEREOF AND NOVEL COMPOUNDS USED IN THE PROCESS | ACTAVIS GROUP PTC EHF. (IS) | 2017-03-02 | — | — | WO | disclosed |