Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4218372 | 0.79 | NPSR1 (0.51) | GRM2NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4233106 | 0.76 | GRM2 (0.49) | GRM2NPSR1NPC1 | |
| SCHEMBL29901097 | 0.72 | GRM2 (0.51) | GRM2NPC1 | |
| SCHEMBL17828279 | 0.70 | GRM2 (0.67) | GRM2NPC1 | |
| SCHEMBL974069 | 0.69 | GRM2 (0.40) | GRM2NPSR1NPC1SMN1; SMN2GPR139 | |
| SCHEMBL29356302 | 0.69 | GRM2 (0.47) | GRM2NPC1 | |
| SCHEMBL4083654 | 0.69 | GRM2 (0.47) | GRM2NPC1 | |
| SCHEMBL19911462 | 0.69 | GRM2 (0.47) | GRM2NPC1GPR139 | |
| SCHEMBL17291776 | 0.69 | GRM2 (0.43) | GRM2NPSR1NPC1SMN1; SMN2 | |
| SCHEMBL19911457 | 0.68 | GRM2 (0.69) | GRM2NPC1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2219687-B1 | PRION DEACTIVATING COMPOSITION AND METHODS OF USING SAME | AMERICAN STERILIZER CO (US) | 2017-03-08 | — | — | EP | claimed |