Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 14/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18547408 | 0.84 | CNR1 (0.56) | CNR2CNR1 | |
| SCHEMBL18547289 | 0.83 | CNR1 (0.47) | CNR2CNR1 | |
| SCHEMBL18546934 | 0.81 | CNR2 (0.51) | CNR2ALOX5CNR1MCHR1 | |
| SCHEMBL18547178 | 0.81 | SOS1 (0.44) | CNR2ALOX5CNR1MCHR1 | |
| SCHEMBL18547399 | 0.80 | CNR1 (0.58) | CNR2CNR1 | |
| Trifluoroacetic Acid SCHEMBL18546915 | 0.80 | CNR1 (0.53) | CNR2CNR1 | |
| SCHEMBL18576149 | 0.80 | MCHR1 (0.39) | CNR2ALOX5CNR1MCHR1 | |
| SCHEMBL18547060 | 0.78 | CNR1 (0.57) | CNR2CNR1 | |
| SCHEMBL18547548 | 0.78 | CNR1 (0.60) | CNR2CNR1MEN1KMT2A | |
| SCHEMBL18547510 | 0.77 | CNR1 (0.44) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017035114-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-02 | — | — | WO | disclosed |