Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18547067 | 0.86 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL18576450 | 0.80 | CNR2 (0.42) | MCHR1CNR1CNR2ALOX5 | |
| SCHEMBL18562614 | 0.77 | LMNA (0.40) | MCHR1NPC1LMNAMAPTRAB9A | |
| SCHEMBL18547493 | 0.76 | CNR2 (0.49) | MCHR1ACSS2NPC1LMNAMAPT | |
| SCHEMBL18547002 | 0.75 | P2RX3 (0.45) | MCHR1NPC1LMNAMAPTRAB9A | |
| SCHEMBL18546889 | 0.75 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL18547177 | 0.74 | ACSS2 (0.43) | MCHR1ACSS2NPC1LMNAMAPT | |
| SCHEMBL18562613 | 0.74 | P2RX3 (0.40) | MCHR1NPC1LMNAMAPTRAB9A | |
| SCHEMBL18547185 | 0.73 | CNR2 (0.46) | MCHR1ACSS2NPC1LMNAMAPT | |
| SCHEMBL18547130 | 0.73 | KCNH2 (0.40) | MCHR1ACSS2NPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017035114-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-02 | — | — | WO | disclosed |