Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980954 | 0.86 | TRPV1 (0.35) | LMNAGAAPOLBNPSR1P2RX7 | |
| SCHEMBL2518670 | 0.86 | EPHX2 (0.38) | LMNAGAAPOLBNPSR1P2RX7 | |
| SCHEMBL981224 | 0.85 | TRPV1 (0.36) | LMNAGAAPOLBNPSR1P2RX7 | |
| SCHEMBL2524299 | 0.84 | MTOR (0.37) | LMNAGAAPOLBNPSR1EPHX2 | |
| SCHEMBL2522173 | 0.84 | MTOR (0.37) | LMNAGAAPOLBNPSR1EPHX2 | |
| SCHEMBL15803905 | 0.84 | EPHX2 (0.38) | LMNAGAAPOLBNPSR1P2RX7 | |
| SCHEMBL979648 | 0.83 | TRPV1 (0.35) | LMNAGAAPOLBNPSR1P2RX7 | |
| SCHEMBL1303776 | 0.83 | EPHX2 (0.35) | LMNAGAAPOLBNPSR1P2RX7 | |
| SCHEMBL12069084 | 0.83 | BTK (0.37) | GAAP2RX7EPHX2HTTCYP2D6 | |
| SCHEMBL980939 | 0.83 | TRPV1 (0.35) | LMNAGAAPOLBNPSR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268754-B2 | Substituted dihydroazole compound and pest control agent | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-09-18 | — | — | US | disclosed |
| US-8242283-B2 | Isoxazoline compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20110172414-A1 | ISOXAZOLINE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-7947715-B2 | Isoxazoline compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-05-24 | — | — | US | disclosed |
| US-20100298558-A1 | SUBSTITUTED DIHYDROAZOLE COMPOUND AND PEST CONTROL AGENT | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-11-25 | — | — | US | disclosed |
| EP-2230230-A1 | SUBSTITUTED DIHYDROAZOLE COMPOUND AND PEST CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2010-09-22 | — | — | EP | disclosed |
| EP-1997813-B1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | NISSAN CHEMICAL IND LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-20090156643-A1 | Substituted isoxazoline compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1997813-A1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2008-12-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172414-A1 | ISOXAZOLINE COMPOUND AND PESTICIDE | HCRTR1, HAX1, CHRM1 | LMNA 1310/4885GAA 4528/4885POLB 4066/4885 |
| US-20090156643-A1 | Substituted isoxazoline compound and pesticide | HCRTR1, CBR1, CHRM1 | LMNA 1943/4885GAA 4547/4885POLB 4278/4885 |
| US-20100298558-A1 | SUBSTITUTED DIHYDROAZOLE COMPOUND AND PEST CONTROL AGENT | H1-0, H1-2, H1-4 | LMNA 1667/4885GAA 4185/4885POLB 4091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.