SCHEMBL18580

SCHEMBL18580

CNS(=O)(=O)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 1/20 0.64
SMN1; SMN2 Q16637 3/20 0.62
GAA P10253 2/20 0.62
CA1 P00915 3/20 0.60
CA2 P00918 3/20 0.60
CA12 O43570 2/20 0.60
CA3 P07451 2/20 0.60
CA4 P22748 2/20 0.60
CA6 P23280 2/20 0.60
CA5A P35218 2/20 0.60
CA7 P43166 2/20 0.60
CA9 Q16790 2/20 0.60
CA13 Q8N1Q1 2/20 0.60
CA14 Q9ULX7 2/20 0.60
CA5B Q9Y2D0 2/20 0.60
MMP1 P03956 1/20 0.58
MMP2 P08253 1/20 0.58
MMP9 P14780 1/20 0.58
MMP8 P22894 1/20 0.58
MMP13 P45452 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11514359 0.97 NR3C2 (0.62) NR3C2SMN1; SMN2GAACA1CA2
Hydrogen Sulfide SCHEMBL27690671 0.97 NR3C2 (0.62) NR3C2SMN1; SMN2GAACA1CA2
Water SCHEMBL27466609 0.97 NR3C2 (0.62) NR3C2SMN1; SMN2GAACA1CA2
Hydrochloric Acid SCHEMBL1807459 0.97 NR3C2 (0.62) NR3C2SMN1; SMN2GAACA1CA2
SCHEMBL27420174 0.93 CA1 (0.59) NR3C2SMN1; SMN2GAACA1CA2
SCHEMBL4050345 0.91 NR3C2 (0.56) NR3C2SMN1; SMN2GAACA1CA2
SCHEMBL28183348 0.89 NR3C2 (0.55) NR3C2SMN1; SMN2GAACA1CA2
SCHEMBL3906959 0.86 NR3C2 (0.61) NR3C2SMN1; SMN2GAACA1CA2
SCHEMBL7629070 0.86 SMN1; SMN2 (0.80) NR3C2SMN1; SMN2GAACA1CA2
SCHEMBL28632075 0.84 NR3C2 (0.50) NR3C2SMN1; SMN2GAACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3051 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630529-B2 GCN2 modulator compounds Alesta Therapeutics BV (NL) 2026-05-19 US claimed
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2026-01-22 US claimed
US-12492193-B2 Pyrazole derivatives for the treatment of cystic fibrosis FONDAZIONE INSTITUTO ITALIANO DI TECNOLOGIA (IT) 2025-12-09 US claimed
US-20250228242-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-07-17 US claimed
CN-120082193-A Corrosion-resistant halogen-free flame-retardant reinforced polyamide material and preparation method thereof 河南格林普斯新材料科技有限公司 2025-06-03 CN claimed
CN-119528773-A N-alkylation method of sulfonamide compound 赣南医科大学 2025-02-28 CN claimed
CN-111699189-B Modulators of beta-3 adrenergic receptors useful for treating or preventing heart failure and disorders associated therewith 艾尼纳制药公司 2025-02-18 CN claimed
US-12208088-B2 Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof GENENTECH, INC. (US) 2025-01-28 US claimed
CN-119233829-A Pharmaceutical composition for preventing, inhibiting or treating symptoms associated with pseudoallergy 学校法人高崎健康福祉大学 2024-12-31 CN claimed
EP-4436959-A1 AMINOHETEROARYL KINASE INHIBITORS Allorion Therapeutics Inc. (US) 2024-10-02 EP claimed
EP-0034432-B1 SULFAMOYL-SUBSTITUTED PHENETHYLAMINE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS, CONTAINING THEM YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1984-04-25 EP claimed
EP-0075434-A2 Cephalosporins, their preparation and their pharmaceutical compositions ICI PHARMA (FR) 1983-03-30 EP claimed
EP-0071370-A2 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them ICI PHARMA (FR) 1983-02-09 EP claimed
EP-0008058-B1 N-AMINO-3,4,5-TRIHYDROXYPIPERIDINES, METHODS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, METHOD FOR THE PRODUCTION OF THE MEDICAMENTS AND ANIMAL FEEDSTUFF CONTAINING SAID COMPOUNDS BAYER AG (DE) 1982-08-18 EP claimed
EP-0055562-A2 Cephalosporin derivatives ICI PHARMA (FR) 1982-07-07 EP claimed
EP-0055099-A1 Penicillin derivatives ICI PHARMA (FR) 1982-06-30 EP claimed
US-4293551-A N-Amino-3,4,5-trihydroxypiperidines, their production and their medicinal use BAYER AKTIENGESELLSCHAFT (DE) 1981-10-06 US claimed
US-4272298-A Process for conditioning a pigment in liquid ammonia CIBA-GEIGY CORPORATION (US) 1981-06-09 US claimed
EP-0008058-A1 N-Amino-3,4,5-trihydroxypiperidines, methods for their preparation, medicaments containing them, method for the production of the medicaments and animal feedstuff containing said compounds BAYER AG (DE) 1980-02-20 EP claimed
US-3966704-A Naphthylazo naphthyl copper complex dyestuffs HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-29 US claimed