Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA3 | P07451 | 2/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.59 |
| ▸ | CA6 | P23280 | 2/20 | 0.59 |
| ▸ | CA5A | P35218 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.59 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18580 | 0.93 | NR3C2 (0.64) | CA1CA2CA12CA3CA4 | |
| Hydrogen Sulfide SCHEMBL27690671 | 0.91 | NR3C2 (0.62) | CA1CA2CA12CA3CA4 | |
| SCHEMBL11514359 | 0.91 | NR3C2 (0.62) | CA1CA2CA12CA3CA4 | |
| Hydrochloric Acid SCHEMBL1807459 | 0.91 | NR3C2 (0.62) | CA1CA2CA12CA3CA4 | |
| Water SCHEMBL27466609 | 0.91 | NR3C2 (0.62) | CA1CA2CA12CA3CA4 | |
| SCHEMBL4050345 | 0.84 | NR3C2 (0.56) | CA1CA2CA12CA3CA4 | |
| SCHEMBL28183348 | 0.83 | NR3C2 (0.55) | CA1CA2CA12CA3CA4 | |
| SCHEMBL3906959 | 0.80 | NR3C2 (0.61) | CA1CA2CA12CA3CA4 | |
| SCHEMBL7629070 | 0.80 | SMN1; SMN2 (0.80) | CA1CA2CA12CA3CA4 | |
| 4-Chloroaniline SCHEMBL2226595 | 0.79 | CA12 (0.67) | CA1CA2CA12CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100356979-C | Integrin expression inhibitors | EISAI CO LTD (JP) | 2007-12-26 | — | — | CN | disclosed |
| CN-1221533-C | Heterobicyclic sulfonamide derivative and sulfonic ester derivative | EISAI CO LTD (JP) | 2005-10-05 | — | — | CN | disclosed |
| CN-1491941-A | Heterobicyclic sulfonamide derivative and sulfonic ester derivative | ������������ʽ���� | 2004-04-28 | — | — | CN | disclosed |
| CN-1079097-C | Heterobicyclic sulfonamide derivatives and sulfonate derivatives | EISAI CO LTD (JP) | 2002-02-13 | — | — | CN | disclosed |
| CN-1114506-A | Heterobicyclic sulfonamide derivatives and sulfonate derivatives | EISAI CO LTD (JP) | 1996-01-03 | — | — | CN | disclosed |