Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 8/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | CDK7 | P50613 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.52 |
| ▸ | PRKX | P51817 | 1/20 | 0.51 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRK5 | P34947 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17034159 | 0.82 | S1PR1 (0.50) | S1PR1S1PR5PDGFRAPRKD3CDK7 | |
| SCHEMBL17048646 | 0.76 | S1PR1 (0.43) | S1PR1S1PR5PDGFRAPRKD3CDK7 | |
| SCHEMBL3042322 | 0.75 | S1PR5 (0.76) | S1PR1S1PR5PDGFRAPRKXPIM1 | |
| SCHEMBL31580790 | 0.73 | MAOB (0.51) | MRGPRX4NR4A2MAOB | |
| SCHEMBL31395035 | 0.72 | S1PR5 (0.82) | S1PR1S1PR5PDGFRAPRKD3CDK7 | |
| SCHEMBL3037632 | 0.71 | S1PR5 (1.00) | S1PR1S1PR5PDGFRAPRKD3CDK7 | |
| SCHEMBL17048680 | 0.70 | SIGMAR1 (0.45) | MRGPRX4NR4A2MAOB | |
| SCHEMBL17027210 | 0.69 | S1PR5 (0.53) | S1PR1S1PR5PDGFRAPRKD3CDK7 | |
| SCHEMBL3042498 | 0.69 | S1PR5 (1.00) | S1PR1S1PR5PDGFRAPRKD3CDK7 | |
| SCHEMBL17034174 | 0.68 | S1PR5 (0.55) | S1PR1S1PR5PDGFRAPRKD3CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170066717-A1 | NEW PHENYLAZETIDINECARBOXYLATE OR -CARBOXAMIDE COMPOUNDS | INVENTIVA (FR) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170066717-A1 | NEW PHENYLAZETIDINECARBOXYLATE OR -CARBOXAMIDE COMPOUNDS | NCOR1, NCOR2, NCOA1 | S1PR1 1142/4885S1PR5 2041/4885PDGFRA 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.