Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18584333 | 0.90 | HPGD (0.46) | ALOX5HPGDKMT2ACYP1A2CYP3A4 | |
| SCHEMBL24378128 | 0.90 | ALOX5 (0.47) | ALOX5HPGDKMT2ACYP1A2CYP3A4 | |
| SCHEMBL18581139 | 0.89 | ALOX5 (0.43) | ALOX5HPGDKMT2ACYP1A2CYP3A4 | |
| SCHEMBL24378127 | 0.89 | HSD17B10 (0.47) | ALOX5HPGDKMT2ACYP1A2CYP3A4 | |
| SCHEMBL31751225 | 0.84 | ALOX5 (0.49) | ALOX5HPGDKMT2ACYP1A2CYP3A4 | |
| SCHEMBL24378020 | 0.83 | KMT2A (0.47) | HPGDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL34474927 | 0.83 | ALOX5 (0.48) | ALOX5HPGDKMT2ACYP1A2CYP3A4 | |
| SCHEMBL13285093 | 0.83 | KMT2A (0.47) | HPGDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18117568 | 0.82 | HPGD (0.46) | HPGDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3932289 | 0.81 | ALOX5 (0.46) | ALOX5HPGDKMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040963-A1 | [6,6] FUSED BICYCLIC HDAC8 INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2017-03-09 | — | — | WO | disclosed |