Gallic Acid Methyl Ester

Gallic Acid Methyl Ester

SCHEMBL18585437

CCCCO.COC(=O)c1cc(O)c(O)c(O)c1

nearest known ligand 0.70

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 2/20 0.70
LMNA P02545 2/20 0.70
KDM4E B2RXH2 1/20 0.70
POLB P06746 1/20 0.70
GAA P10253 1/20 0.70
NFKB1 P19838 1/20 0.70
GFER P55789 1/20 0.70
NFKB2 Q00653 1/20 0.70
RELA Q04206 1/20 0.70
FUT7 Q11130 1/20 0.70
TDP1 Q9NUW8 1/20 0.70
L3MBTL1 Q9Y468 1/20 0.70
ESR1 P03372 3/20 0.61
AKR1C4 P17516 1/20 0.58
AKR1C3 P42330 1/20 0.58
AKR1C2 P52895 1/20 0.58
AKR1C1 Q04828 1/20 0.58
SERPINE1 P05121 4/20 0.50
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gallic Acid Methyl Ester SCHEMBL18585459 0.88 XDH (0.84) XDHLMNAKDM4EPOLBGAA
Gallic Acid Methyl Ester SCHEMBL39513 0.84 KDM4E (1.00) XDHLMNAKDM4EPOLBGAA
Gallic Acid Methyl Ester SCHEMBL28556619 0.82 KDM4E (0.95) XDHLMNAKDM4EPOLBGAA
Gallic Acid Methyl Ester SCHEMBL21543905 0.82 KDM4E (0.95) XDHLMNAKDM4EPOLBGAA
Gallic Acid Methyl Ester SCHEMBL21611341 0.82 KDM4E (0.95) XDHLMNAKDM4EPOLBGAA
Gallic Acid Methyl Ester SCHEMBL28507408 0.82 KDM4E (0.95) XDHLMNAKDM4EPOLBGAA
Gallic Acid SCHEMBL27793308 0.81 KDM4E (0.63) XDHLMNAKDM4EPOLBGAA
SCHEMBL22062348 0.81 XDH (0.61) XDHLMNAKDM4EPOLBGAA
SCHEMBL5157109 0.81 ESR1 (0.62) XDHLMNAKDM4EPOLBGAA
Propyl Gallate SCHEMBL1668822 0.80 ESR1 (0.71) XDHLMNAKDM4EPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3344265-A1 TOPICAL ANTIVIRAL COMPOSITIONS Topical Remedy, LLC (US) 2018-07-11 EP disclosed
WO-2017040844-A1 TOPICAL ANTIVIRAL COMPOSITIONS TOPICAL REMEDY, LLC (US) 2017-03-09 WO disclosed