Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL912359 | 0.80 | HTR2C (0.47) | HTR2CKDM4ETSHRHTR2AHTR2B | |
| SCHEMBL3293431 | 0.80 | HTR2A (0.47) | HTR2CKDM4ETSHRHTR2AHTR2B | |
| SCHEMBL29812920 | 0.80 | HTR2C (0.47) | HTR2CKDM4ETSHRHTR2AHTR2B | |
| SCHEMBL1741315 | 0.80 | KDM1A (0.53) | HTR2CKDM4ETSHRHTR2AHTR2B | |
| SCHEMBL22194113 | 0.80 | KDM4E (0.34) | KDM4ETSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL29625374 | 0.80 | HTR2A (0.47) | HTR2CKDM4ETSHRHTR2AHTR2B | |
| SCHEMBL1739919 | 0.80 | HTR2A (0.47) | HTR2CKDM4ETSHRHTR2AHTR2B | |
| SCHEMBL18587144 | 0.79 | CHRNB2 (0.44) | HTR2CKDM4ETSHR | |
| SCHEMBL22194114 | 0.79 | KDM4E (0.38) | KDM4ETSHRCYP2D6MEN1KMT2A | |
| SCHEMBL1011179 | 0.77 | KDM1A (0.58) | TSHRCYP2D6KDM1AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565850-A1 | POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS | Promerus, LLC (US) | 2019-11-13 | — | — | EP | claimed |
| WO-2018129121-A1 | POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS | PROMERUS, LLC (US) | 2018-07-12 | — | — | WO | claimed |
| EP-3344671-A1 | POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS | Promerus, LLC (US) | 2018-07-11 | — | — | EP | claimed |
| WO-2017040737-A1 | POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS | PROMERUS, LLC (US) | 2017-03-09 | — | — | WO | claimed |