Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.58 |
| ▸ | PDE8B | O95263 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18587976 | 0.91 | YTHDC1 (0.59) | YTHDC1ADORA3ADORA1NPC1RAB9A | |
| SCHEMBL29664960 | 0.91 | YTHDC1 (0.59) | YTHDC1ADORA3ADORA1NPC1RAB9A | |
| SCHEMBL29659519 | 0.89 | YTHDC1 (0.64) | YTHDC1ADORA3ADORA1NPC1RAB9A | |
| SCHEMBL20547190 | 0.89 | YTHDC1 (0.64) | YTHDC1ADORA3ADORA1NPC1RAB9A | |
| SCHEMBL18587515 | 0.84 | YTHDC1 (0.57) | YTHDC1ADORA3ADORA1NPC1RAB9A | |
| SCHEMBL5695023 | 0.84 | YTHDC1 (0.65) | YTHDC1ADORA3ADORA1NPC1RAB9A | |
| SCHEMBL18587529 | 0.81 | YTHDC1 (0.64) | YTHDC1ADORA3ADORA1NPC1RAB9A | |
| SCHEMBL20547426 | 0.81 | NPC1 (0.68) | YTHDC1ADORA3ADORA1NPC1RAB9A | |
| SCHEMBL28433352 | 0.80 | YTHDC1 (0.74) | YTHDC1ADORA3ADORA1NPC1RAB9A | |
| SCHEMBL17902915 | 0.80 | YTHDC1 (0.71) | YTHDC1ADORA3ADORA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341371-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | Univerzita Palackého V Olomouci (CZ) | 2018-07-04 | — | — | EP | claimed |
| WO-2017036434-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2017-03-09 | — | — | WO | claimed |