Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 11/20 | 0.65 |
| ▸ | CHIT1 | Q13231 | 15/20 | 0.51 |
| ▸ | CHIA | Q9BZP6 | 15/20 | 0.51 |
| ▸ | CHI3L1 | P36222 | 8/20 | 0.51 |
| ▸ | CHI3L2 | Q15782 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18607917 | 1.00 | KCNH2 (0.65) | KCNH2CHIT1CHIACHI3L1CHI3L2 | |
| SCHEMBL18607916 | 1.00 | KCNH2 (0.65) | KCNH2CHIT1CHIACHI3L1CHI3L2 | |
| SCHEMBL18607978 | 1.00 | KCNH2 (0.65) | KCNH2CHIT1CHIACHI3L1CHI3L2 | |
| Trifluoroacetic Acid SCHEMBL18577402 | 0.92 | KCNH2 (0.57) | KCNH2CHIT1CHIACHI3L1CHI3L2 | |
| SCHEMBL18608043 | 0.87 | CHIT1 (0.65) | KCNH2CHIT1CHIACHI3L1CHI3L2 | |
| SCHEMBL20629130 | 0.87 | CHIT1 (0.65) | KCNH2CHIT1CHIACHI3L1CHI3L2 | |
| SCHEMBL22901850 | 0.87 | KCNH2 (0.64) | KCNH2CHIT1CHIACHI3L1CHI3L2 | |
| SCHEMBL22901908 | 0.87 | KCNH2 (0.64) | KCNH2CHIT1CHIACHI3L1CHI3L2 | |
| SCHEMBL18589361 | 0.87 | CHIT1 (0.65) | KCNH2CHIT1CHIACHI3L1CHI3L2 | |
| SCHEMBL18608042 | 0.87 | CHIT1 (0.65) | KCNH2CHIT1CHIACHI3L1CHI3L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344616-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-01-09 | — | — | EP | disclosed |
| US-9944624-B2 | Substituted amino triazoles useful as human chitinase inhibitors | Oncoarendi Therapeutics S.A. (PL) | 2018-04-17 | — | — | US | disclosed |
| US-20170066743-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | GALAPAGOS NV (BE) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170066743-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | CHIA, CHIT1, AADAC | KCNH2 3882/4885CHIT1 2/4885CHIA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.