Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL1859360

N#Cc1c[nH]c(C(=O)Nc2ccc(C3CNC(=O)NC3)cc2C2=CCCCC2)n1.O=C(O)C(F)(F)F

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 16/20 0.65
CYP2C9 P11712 1/20 0.60
KIT P10721 4/20 0.51
CYP2C19 P33261 3/20 0.48
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12408087 0.94 CSF1R (0.72) CSF1RCYP2C9KITCYP2C19CYP3A4
Trifluoroacetic Acid SCHEMBL31157981 0.89 CSF1R (0.75) CSF1RCYP2C9KITCYP2C19CYP3A4
Trifluoroacetic Acid SCHEMBL1859712 0.89 CSF1R (0.67) CSF1RCYP2C9KITCYP2C19
Trifluoroacetic Acid SCHEMBL1856490 0.88 CSF1R (0.67) CSF1RCYP2C9KITCYP2C19
Trifluoroacetic Acid SCHEMBL1862324 0.87 CSF1R (0.67) CSF1RCYP2C9KITCYP2C19
SCHEMBL12422506 0.86 CSF1R (0.60) CSF1RCYP2C9KITCYP2C19CYP3A4
SCHEMBL1868772 0.86 CSF1R (0.60) CSF1RCYP2C9KITCYP2C19CYP3A4
Trifluoroacetic Acid SCHEMBL2943105 0.86 CSF1R (0.69) CSF1RCYP2C9KITCYP2C19CYP3A4
Trifluoroacetic Acid SCHEMBL4983287 0.85 CSF1R (0.68) CSF1RCYP2C9KITCYP2C19CYP3A4
SCHEMBL1856332 0.85 CSF1R (0.72) CSF1RCYP2C9KITCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110195960-A1 INHIBITORS OF C-FMS KINASE ILLIG CARL R 2011-08-11 US disclosed
EP-2021335-B1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF C-FMS KINASE JANSSEN PHARMACEUTICA NV (BE) 2011-05-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110195960-A1 INHIBITORS OF C-FMS KINASE MUSK, FRK, FES CSF1R 59/4885CYP2C9 1815/4885KIT 108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.