Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21126658 | 0.81 | P2RX7 (0.55) | P2RX7GRM5RAB9ACCR1CCR8 | |
| SCHEMBL4782704 | 0.81 | RECQL (0.54) | P2RX7GRM5RAB9ACYP1A2TDP1 | |
| SCHEMBL11363955 | 0.81 | RECQL (0.54) | P2RX7GRM5RAB9ACYP1A2TDP1 | |
| SCHEMBL23598517 | 0.80 | MAPT (0.59) | GRM5RAB9ACYP1A2KDM4ETSHR | |
| SCHEMBL17819482 | 0.79 | P2RX7 (0.53) | P2RX7GRM5RAB9ACCR1CCR8 | |
| SCHEMBL11383075 | 0.78 | P2RX7 (0.51) | P2RX7GRM5RAB9ACCR1CCR8 | |
| SCHEMBL20362924 | 0.76 | P2RX7 (0.48) | P2RX7GRM5RAB9ACCR1CCR8 | |
| SCHEMBL13465188 | 0.76 | P2RX7 (0.48) | P2RX7GRM5RAB9ACCR1CCR8 | |
| SCHEMBL2237588 | 0.76 | P2RX7 (0.62) | P2RX7GRM5RAB9ACCR1CCR8 | |
| SCHEMBL1958309 | 0.76 | P2RX7 (0.62) | P2RX7GRM5RAB9ACCR1CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |