Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.46 |
| ▸ | SHBG | P04278 | 7/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13415931 | 0.82 | CYP17A1 (0.59) | CYP19A1ALDH1A1LMNACYP3A4MAPT | |
| SCHEMBL1862462 | 0.81 | SHBG (0.44) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL1859929 | 0.80 | SHBG (0.43) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL1864731 | 0.80 | SHBG (0.43) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL30140884 | 0.78 | SHBG (0.59) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL7703808 | 0.78 | SHBG (0.59) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL2832958 | 0.78 | SHBG (0.59) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL1860492 | 0.78 | CYP19A1 (0.44) | CYP19A1SHBGARPGR | |
| SCHEMBL1868136 | 0.77 | CYP19A1 (0.52) | CYP19A1CYP3A4 | |
| SCHEMBL1861922 | 0.77 | CYP17A1 (0.39) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939517-B2 | 1,4,6-androstatriene-3,17-dione (“ATD”) for therapeutic uses | KNELLER BRUCE W | 2011-05-10 | — | — | US | claimed |
| US-20060154909-A1 | 1,4,6-androstatriene-3,17-dione (\"ATD\") for therapeutic uses | KNELLER BRUCE W | 2006-07-13 | — | — | US | claimed |
| US-7939517-B2 | 1,4,6-androstatriene-3,17-dione (“ATD”) for therapeutic uses | KNELLER BRUCE W | 2011-05-10 | — | — | US | disclosed |
| US-20060154909-A1 | 1,4,6-androstatriene-3,17-dione (\"ATD\") for therapeutic uses | KNELLER BRUCE W | 2006-07-13 | — | — | US | disclosed |