SCHEMBL18595656

SCHEMBL18595656

COc1ncnc2c1ccn2[C@@H]1OC(CO)[C@@H](O)[C@H]1O

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADK P55263 2/20 0.61
SLC29A1 Q99808 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17816361 1.00 ADK (0.61) ADKSLC29A1
SCHEMBL13005619 0.86 PRMT5 (0.46) ADK
SCHEMBL3769782 0.86 PRMT5 (0.46) ADK
SCHEMBL3769785 0.86 PRMT5 (0.46) ADK
SCHEMBL17800853 0.84 ADK (0.64) ADKSLC29A1
SCHEMBL314884 0.84 ADK (0.64) ADKSLC29A1
SCHEMBL18009703 0.84 ADK (0.64) ADKSLC29A1
SCHEMBL17816352 0.84 ADK (0.64) ADKSLC29A1
SCHEMBL18595743 0.84 ADK (0.64) ADKSLC29A1
Immunicillin H SCHEMBL31416024 0.83 ADK (0.65) ADKSLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9586986-B2 Substituted 7-deazapurine ribonucleosides for therapeutic uses INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) 2017-03-07 US disclosed