Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CALML3 | P27482 | 1/20 | 0.46 |
| ▸ | SDHA | P31040 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18595770 | 0.88 | NPC1 (0.43) | MAOBLMNAMAOAPTGS1CALML3 | |
| SCHEMBL18595769 | 0.87 | LMNA (0.48) | MAOBLMNAMAOAPTGS1CALML3 | |
| SCHEMBL483886 | 0.87 | LMNA (0.48) | MAOBLMNAMAOAPTGS1CALML3 | |
| SCHEMBL18595768 | 0.82 | HPGD (0.41) | MAOBLMNAMAOAPTGS1CALML3 | |
| SCHEMBL8425426 | 0.80 | NPC1 (0.50) | MAOBLMNAMAOAPTGS1CALML3 | |
| SCHEMBL19193668 | 0.78 | MAOB (0.66) | MAOBLMNAMAOAPTGS1CALML3 | |
| SCHEMBL483912 | 0.78 | MAOB (0.45) | MAOBLMNAMAOAPTGS1CALML3 | |
| SCHEMBL483665 | 0.78 | LMNA (0.45) | MAOBLMNAMAOAPTGS1CALML3 | |
| SCHEMBL15618875 | 0.76 | NPC1 (0.47) | MAOBLMNAMAOAPTGS1CALML3 | |
| SCHEMBL15618877 | 0.76 | NPC1 (0.47) | MAOBLMNAMAOAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586913-B2 | Processes for the preparation of linezolid using novel intermediates | SYMED LABS LIMITED (IN) | 2017-03-07 | — | — | US | disclosed |