Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL854855 | 0.82 | EPHX1 (0.51) | EPHX1SMN1; SMN2L3MBTL1HPGDRAB9A | |
| SCHEMBL25562305 | 0.76 | EPHX1 (0.54) | EPHX1SMN1; SMN2L3MBTL1HPGDRAB9A | |
| SCHEMBL12963093 | 0.75 | EPHX1 (0.46) | EPHX1SMN1; SMN2L3MBTL1HPGDRAB9A | |
| SCHEMBL11113503 | 0.74 | ALDH1A1 (0.47) | EPHX1SMN1; SMN2L3MBTL1HPGDRAB9A | |
| SCHEMBL2064181 | 0.73 | MAPT (0.54) | EPHX1SMN1; SMN2L3MBTL1HPGDLMNA | |
| SCHEMBL20643916 | 0.73 | EPHX1 (0.43) | EPHX1SMN1; SMN2L3MBTL1HPGDRAB9A | |
| SCHEMBL11117632 | 0.71 | STK17B (0.45) | EPHX1SMN1; SMN2L3MBTL1HPGDRAB9A | |
| SCHEMBL103979 | 0.71 | STK17A (0.55) | EPHX1LMNAALDH1A1KDM4EGAA | |
| SCHEMBL11476807 | 0.70 | EPHX1 (0.50) | EPHX1SMN1; SMN2LMNAALDH1A1ABL1 | |
| SCHEMBL16869986 | 0.70 | SMN1; SMN2 (0.49) | EPHX1SMN1; SMN2L3MBTL1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586978-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2017-03-07 | — | — | US | disclosed |