Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18597214 | 0.96 | KDM4E (0.38) | KDM4ERAB9AABCB1ALDH1A1HSD17B10 | |
| SCHEMBL18597213 | 0.96 | KDM4E (0.38) | KDM4ERAB9AABCB1ALDH1A1HSD17B10 | |
| SCHEMBL18597210 | 0.92 | KDM4E (0.36) | KDM4ERAB9AABCB1MEN1KMT2A | |
| SCHEMBL18597208 | 0.92 | KDM4E (0.36) | KDM4ERAB9AABCB1MEN1KMT2A | |
| SCHEMBL18597248 | 0.89 | KDM4E (0.34) | KDM4ERAB9A | |
| SCHEMBL18597247 | 0.89 | KDM4E (0.34) | KDM4ERAB9A | |
| SCHEMBL19142351 | 0.87 | KDM4E (0.42) | KDM4ERAB9AABCB1ALDH1A1HSD17B10 | |
| SCHEMBL19142327 | 0.86 | RAB9A (0.46) | KDM4ERAB9AABCB1ALDH1A1HSD17B10 | |
| SCHEMBL19142213 | 0.85 | KDM4E (0.40) | KDM4ERAB9AABCB1ALDH1A1HSD17B10 | |
| SCHEMBL19142350 | 0.85 | KDM4E (0.37) | KDM4ERAB9AABCB1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882707-B1 | NOVEL FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE, DISPLAY APPARATUS, IMAGE INFORMATION PROCESSING APPARATUS, LIGHTING SYSTEM, AND IMAGE FORMING APPARATUS HAVING THE COMPOUND | CANON KK (JP) | 2017-03-08 | — | — | EP | disclosed |