Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | ODC1 | P11926 | 3/20 | 0.54 |
| ▸ | HIF1AN | Q9NWT6 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16244791 | 0.92 | HIF1AN (0.60) | NFKB1NFKB2RELAMAPTCYP3A4 | |
| SCHEMBL16244793 | 0.92 | HIF1AN (0.60) | NFKB1NFKB2RELAMAPTCYP3A4 | |
| SCHEMBL14325195 | 0.89 | MAPT (0.55) | NFKB1NFKB2RELAMAPTCYP3A4 | |
| SCHEMBL31376248 | 0.85 | NFKB1 (0.70) | NFKB1NFKB2RELAABCG2ODC1 | |
| SCHEMBL31376237 | 0.84 | NFKB1 (0.69) | NFKB1NFKB2RELAABCG2ODC1 | |
| SCHEMBL31376180 | 0.84 | NFKB1 (0.68) | NFKB1NFKB2RELAMAPTCYP3A4 | |
| SCHEMBL2282019 | 0.80 | MAPT (0.67) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31376169 | 0.79 | HIF1AN (0.65) | NFKB1NFKB2RELAODC1HIF1AN | |
| Pongapinone A SCHEMBL31237719 | 0.78 | HIF1A (0.58) | MAPTCYP3A4HIF1AALDH1A1KDM4E | |
| SCHEMBL31376261 | 0.78 | ODC1 (0.75) | NFKB1NFKB2RELAMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2720693-B1 | CHROMANE-LIKE CYCLIC PRENYLFLAVONOIDS FOR THE MEDICAL INTERVENTION IN NEUROLOGICAL DISORDERS | AIGNER LUDWIG (AT) | 2017-03-08 | — | — | EP | disclosed |