Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.46 |
| ▸ | ODC1 | P11926 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18597480 | 0.90 | HIF1A (0.53) | HSP90AA1CYP19A1HIF1AODC1MAPT | |
| SCHEMBL16867662 | 0.77 | HSP90AA1 (0.68) | HSP90AA1HIF1AODC1HIF1AN | |
| SCHEMBL30040796 | 0.77 | HSP90AA1 (0.50) | HSP90AA1HIF1AODC1HIF1AN | |
| SCHEMBL16244979 | 0.77 | HSP90AA1 (0.50) | HSP90AA1HIF1AODC1HIF1AN | |
| SCHEMBL16245064 | 0.76 | HIF1AN (0.67) | ODC1HIF1AN | |
| SCHEMBL14315437 | 0.76 | HIF1AN (0.67) | ODC1HIF1AN | |
| SCHEMBL16865563 | 0.75 | HSP90AA1 (0.66) | HSP90AA1HIF1AODC1HIF1AN | |
| SCHEMBL3705603 | 0.75 | HSP90AA1 (0.48) | HSP90AA1HIF1AODC1HIF1AN | |
| SCHEMBL19221618 | 0.73 | HSP90AA1 (0.47) | HSP90AA1HIF1AODC1MAPTHIF1AN | |
| SCHEMBL31376261 | 0.72 | ODC1 (0.75) | ODC1MAPTHIF1AN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2720693-B1 | CHROMANE-LIKE CYCLIC PRENYLFLAVONOIDS FOR THE MEDICAL INTERVENTION IN NEUROLOGICAL DISORDERS | AIGNER LUDWIG (AT) | 2017-03-08 | — | — | EP | disclosed |