Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.47 |
| ▸ | ODC1 | P11926 | 3/20 | 0.46 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701446 | 0.88 | HIF1A (0.53) | HSP90AA1PDE4DHIF1ANFKB1NFKB2 | |
| SCHEMBL16244979 | 0.87 | HSP90AA1 (0.50) | HSP90AA1PDE4DHIF1AODC1HIF1AN | |
| SCHEMBL30040796 | 0.87 | HSP90AA1 (0.50) | HSP90AA1PDE4DHIF1AODC1HIF1AN | |
| SCHEMBL19221618 | 0.82 | HSP90AA1 (0.47) | HSP90AA1PDE4DHIF1AODC1HIF1AN | |
| SCHEMBL3706391 | 0.82 | HIF1A (0.49) | HSP90AA1HIF1AODC1CYP3A4 | |
| SCHEMBL31376226 | 0.78 | ODC1 (0.60) | ODC1HIF1ANNFKB1NFKB2RELA | |
| SCHEMBL31376243 | 0.77 | HSP90AA1 (0.51) | HSP90AA1PDE4DHIF1ANFKB1NFKB2 | |
| SCHEMBL21436759 | 0.76 | ODC1 (0.51) | HSP90AA1PDE4DHIF1AODC1HIF1AN | |
| SCHEMBL29466866 | 0.76 | ODC1 (0.51) | HSP90AA1PDE4DHIF1AODC1HIF1AN | |
| SCHEMBL18597480 | 0.76 | HIF1A (0.53) | HSP90AA1HIF1AODC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190187-A1 | FORMULATION FOR ENHANCED DELIVERY OF PHENETHYLAMINE | KNELLER BRUCE W | 2007-08-16 | — | — | US | claimed |
| WO-2010092162-A1 | NEUROACTIVE PLANT EXTRACT FROM HYPERICUM POLYANTHEMUM | UNIVERSITE DE ROUEN (FR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010092162-A1 | NEUROACTIVE PLANT EXTRACT FROM HYPERICUM POLYANTHEMUM | UNIVERSITE DE ROUEN (FR) | 2010-08-19 | — | — | WO | disclosed |
| US-20070190187-A1 | FORMULATION FOR ENHANCED DELIVERY OF PHENETHYLAMINE | KNELLER BRUCE W | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190187-A1 | FORMULATION FOR ENHANCED DELIVERY OF PHENETHYLAMINE | MAOB, PNMT, MAOA | HSP90AA1 3852/4885PDE4D 423/4885HIF1A 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.