Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.41 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNASTAT3LPAR1LPAR3 | |
| SCHEMBL13719969 | 0.87 | ALDH1A1 (0.51) | ALDH1A1LMNASTAT3LPAR1LPAR3 | |
| SCHEMBL18597898 | 0.84 | LPAR1 (0.59) | ALDH1A1LMNASTAT3LPAR1LPAR3 | |
| SCHEMBL14703 | 0.84 | LPAR1 (0.59) | ALDH1A1LMNASTAT3LPAR1LPAR3 | |
| SCHEMBL6783 | 0.80 | GAA (0.46) | ALDH1A1LMNASTAT3LPAR1LPAR3 | |
| SCHEMBL7475 | 0.80 | PTPN1 (0.40) | ALDH1A1LPAR1LPAR3SMN1; SMN2ABCC3 | |
| SCHEMBL6812 | 0.79 | LPAR1 (0.50) | STAT3LPAR1LPAR3ABCC3ABCC4 | |
| SCHEMBL6377 | 0.79 | CNR1 (0.42) | SMN1; SMN2CYP2C9TSHRPOLB | |
| SCHEMBL7105 | 0.78 | ALDH1A1 (0.53) | ALDH1A1LMNASTAT3LPAR1LPAR3 | |
| SCHEMBL7013 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNASTAT3LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483252-B1 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS INC (US) | 2017-03-08 | — | — | EP | disclosed |