Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC3 | O15438 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 3/20 | 0.37 |
| ▸ | EDNRA | P25101 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.35 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11644 | 0.90 | ABCC3 (0.47) | ABCC3ABCC4ABCB11CYP2C8CYP2C9 | |
| SCHEMBL2636512 | 0.84 | LPAR1 (0.55) | ABCC3ABCC4ABCB11CYP2C8CYP2C9 | |
| SCHEMBL18597706 | 0.80 | LPAR1 (0.63) | ABCC3ABCC4ABCB11CYP2C8CYP2C9 | |
| SCHEMBL2272 | 0.78 | LPAR1 (0.40) | ABCC3ABCC4ABCB11CYP2C8CYP2C9 | |
| SCHEMBL2636016 | 0.78 | LPAR1 (0.54) | ABCC3ABCC4ABCB11CYP2C8CYP2C9 | |
| SCHEMBL343602 | 0.77 | LPAR1 (0.77) | ABCC3ABCC4ABCB11CYP2C8CYP2C9 | |
| SCHEMBL12984328 | 0.76 | LPAR1 (0.43) | ABCC3ABCC4ABCB11CYP2C8CYP2C9 | |
| SCHEMBL7404 | 0.76 | LPAR1 (0.61) | ABCC3ABCC4ABCB11CYP2C8CYP2C9 | |
| SCHEMBL12983891 | 0.75 | LPAR1 (0.42) | ABCC3ABCC4ABCB11CYP2C8CYP2C9 | |
| SCHEMBL18597789 | 0.75 | ABCC3 (0.51) | ABCC3ABCC4ABCB11CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483252-B1 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS INC (US) | 2017-03-08 | — | — | EP | disclosed |