Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21974562 | 0.70 | RAB9A (0.48) | — | |
| SCHEMBL18678349 | 0.67 | RAB9A (0.54) | GRM1 | |
| SCHEMBL13685621 | 0.64 | KDM4E (0.41) | GRM1 | |
| SCHEMBL12127924 | 0.64 | CCR1 (0.48) | — | |
| SCHEMBL25933244 | 0.62 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL14420773 | 0.61 | HRH3 (0.46) | — | |
| SCHEMBL25777808 | 0.61 | MEN1 (0.40) | — | |
| SCHEMBL11987587 | 0.61 | HTR2C (0.43) | — | |
| SCHEMBL13774787 | 0.60 | CDC7 (0.32) | — | |
| SCHEMBL12127868 | 0.60 | PARP10 (0.51) | LIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348023-B9 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2017-03-08 | — | — | EP | disclosed |