Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.59 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12666844 | 0.91 | TRPV1 (0.51) | TRPV1MAPK3SCN9A | |
| SCHEMBL1862801 | 0.89 | TRPV1 (0.47) | TRPV1MAPK3SCN9A | |
| SCHEMBL1858241 | 0.86 | TRPV1 (0.58) | TRPV1MAPK3 | |
| SCHEMBL1864049 | 0.85 | TRPV1 (0.46) | TRPV1SCN9A | |
| SCHEMBL1856817 | 0.84 | TRPV1 (0.69) | TRPV1MAPK3 | |
| SCHEMBL1858558 | 0.84 | TRPV1 (0.66) | TRPV1MAPK3SCN9A | |
| SCHEMBL12664963 | 0.82 | TRPV1 (0.50) | TRPV1MAPK3 | |
| SCHEMBL1866310 | 0.80 | TRPV1 (0.66) | TRPV1MAPK3 | |
| SCHEMBL12666701 | 0.79 | TRPV1 (0.42) | TRPV1SCN9A | |
| SCHEMBL1863478 | 0.79 | TRPV1 (0.74) | TRPV1MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935702-B2 | Substituted biaryl quinolin-4-ylamine analogues | NEUROGEN CORPORATION (US) | 2011-05-03 | — | — | US | disclosed |
| US-7935702-B2 | Substituted biaryl quinolin-4-ylamine analogues | NEUROGEN CORPORATION (US) | 2011-05-03 | — | — | US | disclosed |