Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24786175 | 0.76 | CA2 (0.41) | TSHR | |
| SCHEMBL17520047 | 0.72 | — | — | |
| SCHEMBL18821372 | 0.72 | — | — | |
| SCHEMBL15854242 | 0.72 | — | — | |
| SCHEMBL466775 | 0.71 | METAP1 (0.39) | METAP1TSHR | |
| SCHEMBL277889 | 0.70 | CA1 (0.43) | METAP1TSHR | |
| SCHEMBL14613112 | 0.70 | METAP1 (0.38) | METAP1TSHR | |
| SCHEMBL18574298 | 0.69 | CHRM1 (0.43) | METAP1TSHR | |
| SCHEMBL11805982 | 0.68 | CHRM1 (0.50) | METAP1TSHR | |
| SCHEMBL28418575 | 0.67 | TSHR (0.38) | METAP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078003-B1 | ANILINOPIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME (US) | 2017-03-08 | — | — | EP | disclosed |