Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 5/20 | 0.43 |
| ▸ | ACACB | O00763 | 9/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18600381 | 0.92 | ATM (0.42) | ATMACACBNAMPTSYK | |
| SCHEMBL21768658 | 0.92 | ATM (0.38) | ATMACACBSYKACACAPTGES | |
| SCHEMBL21768660 | 0.92 | ATM (0.38) | ATMACACBSYKACACAPTGES | |
| SCHEMBL18574878 | 0.88 | GPR119 (0.44) | — | |
| SCHEMBL18574881 | 0.88 | GPR119 (0.44) | — | |
| SCHEMBL18574924 | 0.88 | GPR119 (0.44) | — | |
| SCHEMBL18600415 | 0.86 | ATM (0.42) | ATMACACBNAMPTSYKPTGES | |
| SCHEMBL18601716 | 0.84 | ATM (0.39) | ATMACACBNAMPTSYKPTGES | |
| SCHEMBL18601286 | 0.83 | ATM (0.39) | ATMACACBNAMPTSYKPTGES | |
| SCHEMBL21768684 | 0.83 | GPR119 (0.36) | ATMACACBSYKPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3138834-B1 | CYCLOHEXENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING METABOLIC DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | HYUNDAI PHARM CO LTD (KR) | 2020-03-04 | — | — | EP | disclosed |
| EP-3138834-A1 | CYCLOHEXENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING METABOLIC DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | Hyundai Pharm Co., Ltd. (KR) | 2017-03-08 | — | — | EP | disclosed |
| US-9126961-B2 | Fluorination process | GE HEALTHCARE LIMITED (GB) | 2015-09-08 | — | — | US | disclosed |