Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10120229 | 0.87 | ITGB2 (0.48) | KMT2AHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8587625 | 0.82 | HTT (0.44) | KMT2AHTTALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7262930 | 0.81 | HTR2C (0.44) | SMN1; SMN2HTR2CHTR2BHTR2A | |
| SCHEMBL15210112 | 0.80 | KMT2A (0.44) | KMT2AHTTLMNAALDH1A1MEN1 | |
| SCHEMBL4782128 | 0.79 | HTR2C (0.41) | KMT2AHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6749672 | 0.77 | NPC1 (0.49) | KMT2AHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL2404056 | 0.76 | HTR2C (0.50) | HTR2CHTR2BHTR2A | |
| Acetic Acid SCHEMBL4628540 | 0.75 | KMT2A (0.55) | KMT2AHTTLMNAALDH1A1SMN1; SMN2 | |
| Acetic Acid SCHEMBL7771699 | 0.75 | KMT2A (0.55) | KMT2AHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL17599087 | 0.74 | GRIK1 (0.41) | ALDH1A1SMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926286-B2 | Vortioxetine intermediate and synthesis process thereof | SHANGHAI SYNCORES TECHNOLOGIES INC. LTD. (CN) | 2018-03-27 | — | — | US | disclosed |
| US-20170088530-A1 | NEW VORTIOXETINE INTERMEDIATE AND SYNTHESIS PROCESS THEREOF | SHANGHAI SYNCORES TECHNOLOGIES INC. LTD. (CN) | 2017-03-30 | — | — | US | disclosed |
| EP-3141543-A1 | NEW VORTIOXETINE INTERMEDIATE AND SYNTHESIS PROCESS THEREOF | Shanghai Syncores Technologies, Inc. (CN) | 2017-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088530-A1 | NEW VORTIOXETINE INTERMEDIATE AND SYNTHESIS PROCESS THEREOF | CYP3A4, CYP4B1, COMT | KMT2A 352/4885HTT 1102/4885LMNA 3947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.