Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 11/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4001768 | 0.85 | HRH4 (0.46) | HRH4HRH3KCNH2NUDT1 | |
| SCHEMBL1775312 | 0.83 | HRH4 (0.53) | HRH4HRH3KCNH2NUDT1 | |
| SCHEMBL1774215 | 0.83 | HRH4 (0.53) | HRH4HRH3KCNH2NUDT1 | |
| SCHEMBL1775871 | 0.83 | HRH4 (0.57) | HRH4HRH3KCNH2NUDT1 | |
| SCHEMBL1776133 | 0.82 | HRH4 (0.64) | HRH4HRH3KCNH2NUDT1 | |
| SCHEMBL1773997 | 0.81 | HRH4 (0.65) | HRH4HRH3KCNH2 | |
| SCHEMBL1773837 | 0.80 | LMNA (0.50) | HRH4HRH3KCNH2 | |
| SCHEMBL1775159 | 0.78 | HRH4 (0.51) | HRH4HRH3KCNH2 | |
| SCHEMBL1775397 | 0.78 | HRH4 (0.54) | HRH4HRH3NUDT1 | |
| SCHEMBL18636560 | 0.78 | HRH4 (0.66) | HRH4HRH3NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966162-B1 | PYRIMIDINE DERIVATIVES | ZIARCO PHARMA LTD (GB) | 2017-03-15 | — | — | EP | disclosed |