Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1774338 | 1.00 | HRH4 (0.40) | HRH4NUDT1KCNH2HRH3 | |
| SCHEMBL18601613 | 0.87 | HRH4 (0.41) | HRH4NUDT1KCNH2HRH3 | |
| SCHEMBL1773647 | 0.87 | HRH4 (0.41) | HRH4NUDT1KCNH2HRH3 | |
| SCHEMBL1774078 | 0.85 | NUDT1 (0.41) | HRH4NUDT1KCNH2HRH3 | |
| SCHEMBL18601615 | 0.85 | NUDT1 (0.41) | HRH4NUDT1KCNH2HRH3 | |
| SCHEMBL1774183 | 0.82 | HRH4 (0.55) | HRH4KCNH2HRH3 | |
| SCHEMBL605001 | 0.82 | HRH4 (0.47) | HRH4KCNH2HRH3 | |
| SCHEMBL18601610 | 0.82 | HRH4 (0.39) | HRH4NUDT1HRH3 | |
| SCHEMBL18601598 | 0.82 | HRH4 (0.41) | HRH4NUDT1 | |
| SCHEMBL1774801 | 0.82 | HRH4 (0.39) | HRH4NUDT1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966162-B1 | PYRIMIDINE DERIVATIVES | ZIARCO PHARMA LTD (GB) | 2017-03-15 | — | — | EP | disclosed |