Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4102268 | 1.00 | KDM1A (0.45) | KDM1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29282704 | 1.00 | KDM1A (0.45) | KDM1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4705113 | 0.90 | PDE4A (0.42) | KDM1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL26627498 | 0.83 | KDM1A (0.45) | KDM1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14927315 | 0.81 | PDE4A (0.44) | KDM1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3747054 | 0.81 | PDE4A (0.44) | KDM1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL625914 | 0.81 | PDE4A (0.44) | KDM1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8276850 | 0.81 | PDE4A (0.44) | KDM1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18618732 | 0.81 | PDE4A (0.44) | KDM1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17977215 | 0.80 | ROCK2 (0.47) | KDM1APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027017-A | BRM inhibitor | 苏州信诺维医药科技股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| EP-1688418-B1 | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARM INC (US) | 2017-03-15 | — | — | EP | disclosed |