Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 4/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318892 | 0.85 | MEN1 (0.49) | MEN1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL318219 | 0.75 | MEN1 (0.54) | MEN1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL318397 | 0.71 | MEN1 (0.57) | MEN1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL318780 | 0.69 | MEN1 (0.69) | MEN1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL318752 | 0.69 | MEN1 (0.51) | MEN1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18601829 | 0.68 | KCNH2 (0.44) | MEN1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL319063 | 0.67 | MEN1 (0.54) | MEN1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL318647 | 0.67 | MEN1 (0.51) | MEN1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL319344 | 0.67 | LMNA (0.42) | MEN1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL318573 | 0.66 | KCNH2 (0.56) | MEN1TP53CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3138841-A1 | D2 ANTAGONISTS, METHODS OF SYNTHESIS AND METHODS OF USE | Altos Therapeutics, LLC (US) | 2017-03-08 | — | — | EP | disclosed |