Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12572278 | 0.84 | PRCP (0.44) | PRCPTLR2DPP7DPP4DPP8 | |
| SCHEMBL10030565 | 0.84 | NOS2 (0.42) | PRCPTLR2DPP7DPP4DPP8 | |
| SCHEMBL8009501 | 0.81 | PRCP (0.46) | PRCPTLR2DPP7DPP4DPP8 | |
| SCHEMBL10826223 | 0.81 | PRCP (0.46) | PRCPTLR2DPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL28098040 | 0.80 | PRCP (0.45) | PRCPTLR2DPP7DPP4DPP8 | |
| SCHEMBL15622836 | 0.80 | PRCP (0.39) | PRCPTLR2DPP7DPP4DPP8 | |
| SCHEMBL4565393 | 0.80 | NOS2 (0.38) | PRCPTLR2DPP7DPP4DPP8 | |
| SCHEMBL28049477 | 0.80 | NOS2 (0.38) | PRCPTLR2DPP7DPP4DPP8 | |
| SCHEMBL4565392 | 0.80 | NOS2 (0.38) | PRCPTLR2DPP7DPP4DPP8 | |
| SCHEMBL1387029 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054992-B1 | PROTEIN-POLYMER-DRUG CONJUGATES | ASANA BIOSCIENCES LLC (US) | 2019-08-14 | — | — | EP | disclosed |
| EP-3054991-B1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS INC (US) | 2019-04-03 | — | — | EP | disclosed |
| EP-2931316-B1 | HYDROXYL-POLYMER-DRUG-PROTEIN CONJUGATES | MERSANA THERAPEUTICS INC (US) | 2019-02-20 | — | — | EP | disclosed |
| EP-2928504-B1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS INC (US) | 2019-02-20 | — | — | EP | disclosed |
| EP-2717916-B1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS INC (US) | 2017-03-08 | — | — | EP | disclosed |