Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12891389 | 1.00 | MAPT (0.71) | MAPTMAPK1TDP1DRD2DRD3 | |
| Homopterocarpin SCHEMBL12998414 | 0.93 | MAPT (0.80) | MAPTMAPK1TDP1DRD2DRD3 | |
| Homopterocarpin SCHEMBL12810803 | 0.93 | MAPT (0.80) | MAPTMAPK1TDP1DRD2DRD3 | |
| Homopterocarpin SCHEMBL12810250 | 0.93 | MAPT (0.80) | MAPTMAPK1TDP1DRD2DRD3 | |
| Homopterocarpin SCHEMBL31237481 | 0.93 | MAPT (0.80) | MAPTMAPK1TDP1DRD2DRD3 | |
| Homopterocarpin SCHEMBL29366996 | 0.93 | MAPT (0.80) | MAPTMAPK1TDP1DRD2DRD3 | |
| SCHEMBL12810063 | 0.86 | MAPT (0.70) | MAPTMAPK1TDP1DRD2DRD3 | |
| SCHEMBL31039664 | 0.86 | MAPT (0.70) | MAPTMAPK1TDP1DRD2DRD3 | |
| SCHEMBL12912390 | 0.86 | MAPT (0.70) | MAPTMAPK1TDP1DRD2DRD3 | |
| SCHEMBL29572230 | 0.86 | MAPT (0.70) | MAPTMAPK1TDP1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2301520-B1 | Oxidative dye | HENKEL AG & CO KGAA (DE) | 2017-03-08 | — | — | EP | disclosed |