Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Homopterocarpin SCHEMBL31237481 | 0.93 | MAPT (0.80) | MAPTMAPK1TDP1DRD2DRD3 | |
| Homopterocarpin SCHEMBL12998414 | 0.93 | MAPT (0.80) | MAPTMAPK1TDP1DRD2DRD3 | |
| Homopterocarpin SCHEMBL12810250 | 0.93 | MAPT (0.80) | MAPTMAPK1TDP1DRD2DRD3 | |
| Homopterocarpin SCHEMBL12810803 | 0.93 | MAPT (0.80) | MAPTMAPK1TDP1DRD2DRD3 | |
| Homopterocarpin SCHEMBL29366996 | 0.93 | MAPT (0.80) | MAPTMAPK1TDP1DRD2DRD3 | |
| SCHEMBL18602053 | 0.86 | MAPT (0.71) | MAPTMAPK1TDP1DRD2DRD3 | |
| SCHEMBL12891389 | 0.86 | MAPT (0.71) | MAPTMAPK1TDP1DRD2DRD3 | |
| SCHEMBL12912390 | 0.85 | MAPT (0.70) | MAPTMAPK1TDP1DRD2DRD3 | |
| SCHEMBL19999732 | 0.85 | MAPT (0.70) | MAPTMAPK1TDP1DRD2DRD3 | |
| SCHEMBL72476 | 0.85 | MAPT (0.70) | MAPTMAPK1TDP1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633203-B2 | Use of pterocarpans as active anti-cellulite ingredients | SYMRISE AG (DE) | 2014-01-21 | — | — | US | disclosed |
| US-8633203-B2 | Use of pterocarpans as active anti-cellulite ingredients | SYMRISE AG (DE) | 2014-01-21 | — | — | US | disclosed |
| EP-2295031-A2 | Use of pterocarpans as anti-cellulite agents | Symrise AG (DE) | 2011-03-16 | — | — | EP | disclosed |
| US-20110034486-A1 | USE OF PTEROCARPANS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE GMBH & CO., KG (DE) | 2011-02-10 | — | — | US | disclosed |
| US-20110034486-A1 | USE OF PTEROCARPANS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE GMBH & CO., KG (DE) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034486-A1 | USE OF PTEROCARPANS AS ACTIVE ANTI-CELLULITE INGREDIENTS | FABP4, PLIN1, CPT1B | MAPT 4747/4885MAPK1 767/4885TDP1 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.