Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 2/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2808451 | 0.88 | MEN1 (0.35) | CTDSP1MEN1KMT2ACYP1A2P2RX7 | |
| SCHEMBL2808449 | 0.88 | MEN1 (0.35) | CTDSP1MEN1KMT2ACYP1A2P2RX7 | |
| SCHEMBL2804900 | 0.83 | SMN1; SMN2 (0.38) | CTDSP1MEN1KMT2ACYP1A2P2RX7 | |
| SCHEMBL185594 | 0.83 | SMN1; SMN2 (0.38) | CTDSP1MEN1KMT2ACYP1A2P2RX7 | |
| SCHEMBL198810 | 0.83 | SMN1; SMN2 (0.38) | CTDSP1MEN1KMT2ACYP1A2P2RX7 | |
| SCHEMBL2812345 | 0.81 | POLB (0.43) | CTDSP1MEN1KMT2ACYP1A2SCN9A | |
| SCHEMBL185730 | 0.80 | BDKRB1 (0.35) | MEN1KMT2ACYP1A2P2RX7SSTR4 | |
| SCHEMBL13128471 | 0.79 | CTDSP1 (0.39) | CTDSP1P2RX7KCNH2SCN5ASCN9A | |
| SCHEMBL2806170 | 0.79 | CTDSP1 (0.35) | CTDSP1MEN1KMT2ACYP1A2P2RX7 | |
| SCHEMBL185234 | 0.79 | GAA (0.35) | CTDSP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |
| EP-2401256-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097372-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |