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SCHEMBL18603003

SCHEMBL18603003

O=C1OC2C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)OC3CC32O1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 17/20 0.40
▸ POLA1 P09884 2/20 0.39
▸ POLB P06746 1/20 0.39
▸ POLD1 P28340 1/20 0.39
▸ P2RY4 P51582 5/20 0.38
▸ P2RY6 Q15077 1/20 0.37
▸ P2RX3 P56373 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18603004 0.77 P2RY2 (0.37) P2RY2POLA1POLBPOLD1P2RY4
SCHEMBL23996237 0.74 P2RY2 (0.46) P2RY2POLA1P2RY4P2RX3
SCHEMBL10239207 0.68 P2RY2 (0.41) P2RY2POLA1POLBPOLD1P2RY4
SCHEMBL24913571 0.68 P2RY2 (0.41) P2RY2POLA1POLBPOLD1P2RY4
SCHEMBL16270912 0.68 P2RY2 (0.41) P2RY2POLA1POLBPOLD1P2RY4
SCHEMBL23424112 0.68 P2RY2 (0.41) P2RY2POLA1POLBPOLD1P2RY4
SCHEMBL272204 0.68 P2RY2 (0.39) P2RY2POLA1POLBPOLD1P2RY4
SCHEMBL300769 0.68 P2RY2 (0.39) P2RY2POLA1POLBPOLD1P2RY4
SCHEMBL15688652 0.67 P2RY2 (0.47) P2RY2POLA1P2RY4
SCHEMBL7211931 0.67 P2RY2 (0.47) P2RY2POLA1P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2294076-B1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED REPLICATION OF NUCLEIC ACID TRILINK BIOTECHNOLOGIES (US) 2017-03-08 — — EP disclosed