SCHEMBL10239207

SCHEMBL10239207

BC1CC(O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 16/20 0.41
P2RY4 P51582 5/20 0.41
FBP1 P09467 1/20 0.39
POLA1 P09884 2/20 0.38
POLB P06746 1/20 0.37
POLD1 P28340 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23424112 1.00 P2RY2 (0.41) P2RY2P2RY4FBP1POLA1POLB
SCHEMBL24913571 1.00 P2RY2 (0.41) P2RY2P2RY4FBP1POLA1POLB
SCHEMBL16270912 1.00 P2RY2 (0.41) P2RY2P2RY4FBP1POLA1POLB
SCHEMBL4149125 0.91 P2RY2 (0.36) P2RY2P2RY4POLA1
SCHEMBL12592848 0.91 P2RY2 (0.39) P2RY2P2RY4FBP1POLA1POLB
SCHEMBL12413504 0.85 P2RY2 (0.34) P2RY2P2RY4FBP1
SCHEMBL7211931 0.85 P2RY2 (0.47) P2RY2P2RY4FBP1POLA1
SCHEMBL15688652 0.85 P2RY2 (0.47) P2RY2P2RY4FBP1POLA1
SCHEMBL28292026 0.85 P2RY2 (0.47) P2RY2P2RY4FBP1POLA1
SCHEMBL18411628 0.85 FBP1 (0.55) FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210164040-A1 CONFORMATIONAL PROBES AND METHODS FOR SEQUENCING NUCLEIC ACIDS ILLUMINA, INC. (US) 2021-06-03 US disclosed
US-10837056-B2 Conformational probes and methods for sequencing nucleic acids ILLUMINA, INC. (US) 2020-11-17 US disclosed
US-9394331-B2 2′-spiro-nucleosides and derivatives thereof useful for treating hepatitis C virus and dengue virus infections GILEAD PHARMASSET LLC (US) 2016-07-19 US disclosed
US-8980558-B2 Methods, compositions and kits for the improved detection of small RNA molecules KUTYAVIN IGOR VASSILY (US) 2015-03-17 US disclosed
US-8980558-B2 Methods, compositions and kits for the improved detection of small RNA molecules KUTYAVIN IGOR VASSILY (US) 2015-03-17 US disclosed
EP-2198059-B1 METHODS FOR THE IMPROVED DETECTION OF SMALL RNA MOLECULES KUTYAVIN IGOR VASSILY (US) 2014-12-03 EP disclosed
US-8841275-B2 2′-spiro-nucleosides and derivatives thereof useful for treating hepatitis C virus and dengue virus infections GILEAD PHARMASSET LLC (US) 2014-09-23 US disclosed
US-20140170666-A1 METHODS, COMPOSITIONS AND KITS FOR THE IMPROVED DETECTION OF SMALL RNA MOLECULES KUTYAVIN IGOR VASSILY (US) 2014-06-19 US disclosed
US-20140170666-A1 METHODS, COMPOSITIONS AND KITS FOR THE IMPROVED DETECTION OF SMALL RNA MOLECULES KUTYAVIN IGOR VASSILY (US) 2014-06-19 US disclosed
US-8637276-B2 Methods, compositions and kits for the improved detection of small RNA molecules KUTYAVIN IGOR VASSILY (US) 2014-01-28 US disclosed
US-7678892-B2 Dye-labeled ribonucleotide triphosphates APPLIED BIOSYSTEMS, LLC (US) 2010-03-16 US disclosed
US-7678892-B2 Dye-labeled ribonucleotide triphosphates APPLIED BIOSYSTEMS, LLC (US) 2010-03-16 US disclosed
WO-2009048928-A1 METHODS, COMPOSITIONS AND KITS FOR THE IMPROVED DETECTION OF SMALL RNA MOLECULES KUTYAVIN IGOR VASSILY (US) 2009-04-16 WO disclosed
US-20070293662-A1 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-12-20 US disclosed
US-20070293662-A1 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-12-20 US disclosed
WO-2007127992-A2 USE OF BASE-MODIFIED DEOXYNUCLEOSIDE TRIPHOSPHATES KUTYAVIN IGOR (US) 2007-11-08 WO disclosed
US-20070254298-A1 ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHOD OF DNA SEQUENCING AND FRAGMENT ANALYSIS APPLERA CORPORATION, APPLIED BIOSYSTEMS GROUP (US) 2007-11-01 US disclosed
US-20070254298-A1 ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHOD OF DNA SEQUENCING AND FRAGMENT ANALYSIS APPLERA CORPORATION, APPLIED BIOSYSTEMS GROUP (US) 2007-11-01 US disclosed
US-7262029-B2 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-08-28 US disclosed
US-7262029-B2 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254298-A1 ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHOD OF DNA SEQUENCING AND FRAGMENT ANALYSIS CHRNB3, CHRNB4, SPR P2RY2 3565/4885P2RY4 3008/4885FBP1 387/4885
US-20070293662-A1 Dye-labeled ribonucleotide triphosphates DUT, POLRMT, SAMHD1 P2RY2 806/4885P2RY4 431/4885FBP1 1156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.