SCHEMBL18603045

SCHEMBL18603045

C=Cn1c2c(c3ccccc31)C=CC(C)C2

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 1/20 0.30
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24305760 0.82 HTR6 (0.34) HRH1HTR6
SCHEMBL19904856 0.79 HTR2A (0.43)
SCHEMBL24200862 0.78
SCHEMBL19268883 0.75 MAPT (0.37) HTR6
SCHEMBL18594805 0.75 BRD4 (0.34)
SCHEMBL29317543 0.75 KDM4E (0.45)
SCHEMBL18872338 0.75
SCHEMBL18533187 0.73 KDM4E (0.39)
SCHEMBL18872775 0.72 KDM4E (0.31)
SCHEMBL19676767 0.72 DDB1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2993520-B1 RESIST COMPOSITION AND PATTERNING PROCESS SHINETSU CHEMICAL CO (JP) 2017-03-08 EP disclosed