SCHEMBL1860331

SCHEMBL1860331

CC(C)(C)N(C(=O)O)c1cccc(C=O)n1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FGFR4 P22455 3/20 0.41
TERT O14746 15/20 0.36
POLB P06746 1/20 0.32
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30602604 0.83 FGFR4 (0.41) FGFR4MEN1KMT2A
SCHEMBL69183 0.79 CLK1 (0.36) POLBMEN1HTTKMT2AL3MBTL1
SCHEMBL15391233 0.78 FGFR4 (0.45) FGFR4TERT
SCHEMBL550049 0.78 CYP3A4 (0.39) POLBMEN1KMT2AL3MBTL1
SCHEMBL1861969 0.75 POLB (0.35) POLBMEN1HTTKMT2AL3MBTL1
SCHEMBL16535224 0.75 PIM1 (0.37) POLBHTTKMT2A
SCHEMBL16535487 0.74 HCRTR1 (0.37) POLB
SCHEMBL1693909 0.74 POLB (0.34) POLBMEN1HTTKMT2AL3MBTL1
SCHEMBL1942910 0.72 FGFR4 (0.45) FGFR4TERT
SCHEMBL28462362 0.72 FGFR4 (0.46) FGFR4TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110105566-A1 FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105566-A1 FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES HAAO, CYP51A1, HPD FGFR4 1323/4885TERT 2225/4885POLB 4360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.