Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 20/20 | 1.00 |
| ▸ | SLC22A12 | Q96S37 | 19/20 | 1.00 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18585179 | 0.86 | SLC22A12 (0.76) | XDHSLC22A12CYP2C8CYP2C9 | |
| SCHEMBL18607439 | 0.82 | XDH (0.69) | XDHSLC22A12CYP2C8CYP2C9 | |
| SCHEMBL18607227 | 0.81 | XDH (0.69) | XDHSLC22A12CYP2C8CYP2C9 | |
| SCHEMBL18607206 | 0.81 | XDH (1.00) | XDHSLC22A12 | |
| SCHEMBL18607433 | 0.79 | XDH (0.69) | XDHSLC22A12CYP2C8CYP2C9 | |
| SCHEMBL4257583 | 0.79 | SLC22A12 (0.64) | XDHSLC22A12CYP2C8CYP2C9 | |
| SCHEMBL18607198 | 0.78 | XDH (0.64) | XDHSLC22A12CYP2C8CYP2C9 | |
| SCHEMBL18607214 | 0.78 | XDH (1.00) | XDHSLC22A12CYP2C8CYP2C9 | |
| SCHEMBL18607217 | 0.77 | SLC22A12 (1.00) | XDHSLC22A12CYP2C8CYP2C9 | |
| SCHEMBL18607219 | 0.76 | XDH (1.00) | XDHSLC22A12CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344604-B1 | CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-11-04 | — | — | EP | disclosed |
| EP-3344604-B1 | CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-11-04 | — | — | EP | disclosed |
| CN-106478500-B | Carboxylic acid substituted (hetero) aromatic ring derivatives, and preparation method and application thereof | 广东东阳光药业有限公司 | 2020-02-11 | — | — | CN | disclosed |
| US-10266496-B2 | Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-04-23 | — | — | US | disclosed |
| US-10266496-B2 | Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-04-23 | — | — | US | disclosed |
| WO-2017036404-A1 | CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266496-B2 | Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof | XDH, ABCG2, SLC7A1 | XDH 1/4885SLC22A12 314/4885CYP2C8 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.