Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.63 |
| ▸ | ESR1 | P03372 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.59 |
| ▸ | ACR | P10323 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18393365 | 0.95 | ESR2 (0.69) | ESR2ESR1KMT2AMEN1CASP3 | |
| SCHEMBL13074785 | 0.90 | ESR1 (0.53) | ESR2ESR1KMT2AMEN1CASP3 | |
| SCHEMBL21681863 | 0.90 | ESR1 (0.56) | ESR2ESR1KMT2AMEN1CASP3 | |
| SCHEMBL14679430 | 0.89 | KMT2A (0.63) | ESR2ESR1KMT2AMEN1CASP3 | |
| SCHEMBL7861539 | 0.88 | SMN1; SMN2 (0.66) | ESR2ESR1KMT2AMEN1PRSS1 | |
| SCHEMBL9683108 | 0.88 | SMN1; SMN2 (0.66) | ESR2ESR1KMT2AMEN1PRSS1 | |
| SCHEMBL27595092 | 0.88 | PRSS1 (0.72) | ESR2ESR1KMT2AMEN1CASP3 | |
| SCHEMBL18121569 | 0.88 | SMN1; SMN2 (0.66) | ESR2ESR1KMT2AMEN1PRSS1 | |
| SCHEMBL13822043 | 0.88 | SMN1; SMN2 (0.66) | ESR2ESR1KMT2AMEN1PRSS1 | |
| SCHEMBL16550074 | 0.88 | SMN1; SMN2 (0.66) | ESR2ESR1KMT2AMEN1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170066967-A1 | POLYMERIZABLE COMPOSITION COMPRISING COMPOUND HAVING MESOGENIC GROUP, AND POLYMER THEREOF | DIC CORPORATION (JP) | 2017-03-09 | — | — | US | disclosed |