SCHEMBL16550074

SCHEMBL16550074

COc1ccc(C(=O)Oc2ccc(C(=O)Oc3ccc(O)cc3)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.66
▸ LMNA P02545 2/20 0.66
▸ CYP1A2 P05177 1/20 0.66
▸ CYP2C9 P11712 1/20 0.66
▸ CYP2C19 P33261 1/20 0.66
▸ ESR2 Q92731 3/20 0.63
▸ CA1 P00915 2/20 0.62
▸ CA2 P00918 2/20 0.62
▸ MAPT P10636 5/20 0.61
▸ KMT2A Q03164 5/20 0.61
▸ GFER P55789 1/20 0.61
▸ PRSS1 P07477 1/20 0.61
▸ ACR P10323 1/20 0.61
▸ RAB9A P51151 2/20 0.59
▸ NPC1 O15118 1/20 0.59
▸ CA12 O43570 1/20 0.59
▸ CA7 P43166 1/20 0.59
▸ CA9 Q16790 1/20 0.59
▸ CA14 Q9ULX7 1/20 0.59
▸ LTA4H P09960 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9683108 1.00 SMN1; SMN2 (0.66) SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19
SCHEMBL13822043 1.00 SMN1; SMN2 (0.66) SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19
SCHEMBL18121569 1.00 SMN1; SMN2 (0.66) SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19
SCHEMBL7861539 1.00 SMN1; SMN2 (0.66) SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19
SCHEMBL8983994 0.95 ESR2 (0.66) SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19
SCHEMBL14877848 0.95 ESR2 (0.66) SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19
SCHEMBL22109034 0.95 ESR2 (0.66) SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19
SCHEMBL14545002 0.95 ESR2 (0.66) SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19
SCHEMBL14877890 0.95 ESR2 (0.66) SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19
SCHEMBL12633718 0.95 ESR2 (0.66) SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170305930-A1 OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-26 — — US disclosed
US-20170306237-A1 COMPOSITION, AND OPTICAL FILM INCLUDING THE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-26 — — US disclosed
US-20170269271-A1 ELLIPTICALLY POLARIZING PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-21 — — US disclosed
US-20170242169-A1 DICHROIC DYE COMPOUND, POLARIZING FILM, AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-24 — — US disclosed
US-20170240810-A1 DICHROIC DYE COMPOUND, POLARIZING FILM, AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-24 — — US disclosed
US-20170226071-A1 DICHROIC DYE COMPOUND, POLARIZING FILM, AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-10 — — US disclosed
US-9644148-B2 Liquid Crystal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-09 — — US disclosed
US-20170123124-A1 POLARIZING PLATE AND DISPLAY DEVICE EQUIPPED WITH THE POLARIZING PLATE, AS WELL AS PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-04 — — US disclosed
US-20170121605-A1 COMPOSITION AND POLARIZING FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-04 — — US disclosed
US-9599759-B2 Patterned polarizing film and its production process SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-21 — — US disclosed
US-9540567-B2 Polymerizable liquid crystal composition and optically anisotropic body JNC CORPORATION (JP) 2017-01-10 — — US disclosed
US-9507068-B2 Method for producing elongate polarizer plate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-11-29 — — US disclosed
US-20160289562-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC BODY JNC CORPORATION (JP) 2016-10-06 — — US disclosed
US-9442232-B2 Optically anisotropic sheet SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-09-13 — — US disclosed
US-9421572-B2 Optically absorptive anisotropic film, three-dimensional optically absorptive anisotropic film and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-23 — — US disclosed
US-20150378068-A1 OPTICALLY ABSORPTIVE ANISOTROPIC FILM, THREE-DIMENSIONAL OPTICALLY ABSORPTIVE ANISOTROPIC FILM AND METHOD FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-31 — — US disclosed
US-20150337203-A1 COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-26 — — US disclosed
US-20150301251-A1 PATTERNED POLARIZING FILM AND ITS PRODUCTION PROCESS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-22 — — US disclosed
US-20150226895-A1 METHOD FOR PRODUCING ELONGATE POLARIZER PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-08-13 — — US disclosed
US-20150062505-A1 OPTICALLY ANISOTROPIC SHEET SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-03-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170226071-A1 DICHROIC DYE COMPOUND, POLARIZING FILM, AND USES THEREOF CRY1, C5, C9 SMN1; SMN2 4054/4885LMNA 410/4885CYP1A2 57/4885
US-20150337203-A1 COMPOSITION CRY1, CRY2, C5 SMN1; SMN2 2452/4885LMNA 465/4885CYP1A2 336/4885
US-20170305930-A1 OPTICAL FILM CDH1, CRY1, CRY2 SMN1; SMN2 3065/4885LMNA 1391/4885CYP1A2 920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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