Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15146119 | 0.88 | TAAR1 (0.41) | SLC6A2TAAR1LMNACYP2D6ESR1 | |
| SCHEMBL14447086 | 0.83 | PTGS1 (0.57) | SLC6A2LMNACYP2C19CYP1A2SMN1; SMN2 | |
| SCHEMBL12309927 | 0.83 | ESR1 (0.61) | SLC6A2LMNAESR1CYP3A4TSHR | |
| SCHEMBL13809203 | 0.81 | ESR1 (0.43) | SLC6A2TAAR1HIF1AESR1CYP3A4 | |
| SCHEMBL13078449 | 0.81 | ESR1 (0.43) | TAAR1CYP1A2SMN1; SMN2ESR1ALDH1A1 | |
| SCHEMBL15457714 | 0.81 | ESR1 (0.43) | SLC6A2ESR1TSHRPPARGPPARA | |
| SCHEMBL15443987 | 0.81 | ESR1 (0.43) | TAAR1TRPA1SMN1; SMN2ESR1ALDH1A1 | |
| SCHEMBL15443986 | 0.79 | ESR1 (0.42) | CYP2D6CYP1A2ESR1CYP3A4 | |
| SCHEMBL881459 | 0.79 | ESR1 (0.42) | TAAR1LMNAESR1ALDH1A1 | |
| SCHEMBL12224660 | 0.79 | ESR1 (0.42) | SLC6A2LMNATRPA1ESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828366-B2 | Bicyclic derivatives and pharmaceutical composition including the same | HANMI PHARM. CO., LTD. (KR) | 2017-11-28 | — | — | US | disclosed |
| US-20170066750-A1 | BICYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | HANMI PHARM. CO., LTD. (KR) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170066750-A1 | BICYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | SLC5A1, SLC5A2, GPR119 | SLC6A2 259/4885TAAR1 4466/4885LMNA 3235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.