SCHEMBL186095

SCHEMBL186095

Nc1cc(S(=O)(=O)O)cc2cc(S(=O)(=O)O)c(N=Nc3ccccc3)c(O)c12.[Na].[Na]

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHLPP2 Q6ZVD8 2/20 0.70
CYP1A2 P05177 3/20 0.65
MEN1 O00255 1/20 0.65
HTT P42858 1/20 0.65
KMT2A Q03164 1/20 0.65
ENPP2 Q13822 7/20 0.63
SUMO2 P61956 1/20 0.56
SUMO1 P63165 1/20 0.56
SENP7 Q9BQF6 1/20 0.56
SENP2 Q9HC62 1/20 0.56
CYP2C9 P11712 1/20 0.55
MAPK1 P28482 1/20 0.55
DNASE1L3 Q13609 1/20 0.55
PRMT1 Q99873 2/20 0.55
PRMT3 O60678 1/20 0.48
EP300 Q09472 1/20 0.48
PRMT6 Q96LA8 1/20 0.48
NT5E P21589 1/20 0.48
POLB P06746 1/20 0.48
CYP2D6 P10635 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL344209 1.00 PHLPP2 (0.70) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL113323 1.00 PHLPP2 (0.70) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL29377534 1.00 PHLPP2 (0.70) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL19513949 0.99 PHLPP2 (0.68) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL27752533 0.99 PHLPP2 (0.68) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL186093 0.99 PHLPP2 (0.68) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL7065494 0.93 PHLPP2 (0.72) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL16675030 0.92 PHLPP2 (0.61) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL19513948 0.91 PHLPP2 (0.62) PHLPP2CYP1A2MEN1HTTKMT2A
SCHEMBL14493380 0.90 PHLPP2 (0.63) PHLPP2CYP1A2MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2930126-B1 Fashionable aerosol dye HENKEL AG & CO KGAA (DE) 2019-10-09 EP claimed
EP-3229918-B1 COMPOSITION AND PROCEDURE FOR TREATING KERATINIC FIBERS WITH FLASH EVAPORATION HENKEL AG & CO KGAA (DE) 2024-03-13 EP disclosed
WO-2023228870-A1 COMPOSITION FOR COLORING KERATIN FIBERS L'OREAL (FR) 2023-11-30 WO disclosed
US-20230051189-A1 COSMETIC PROCESS USING MICRONEEDLE SHEET L'OREAL (FR) 2023-02-16 US disclosed
WO-2021125067-A1 COSMETIC PROCESS USING MICRONEEDLE SHEET L'OREAL (FR) 2021-06-24 WO disclosed
US-10259946-B1 Sealing agents, methods of making and uses thereof James Hardie Technology Limited (IE) 2019-04-16 US disclosed
US-10111508-B2 Composition and method for treating keratin fibers with flash evaporation HENKEL AG & CO. KGAA (DE) 2018-10-30 US disclosed
US-20170273424-A1 COMPOSITION AND METHOD FOR TREATING KERATIN FIBERS WITH FLASH EVAPORATION HENKEL AG & CO. KGAA (DE) 2017-09-28 US disclosed
US-9173829-B2 Compositions for dyeing keratin fibers HENKEL AG & CO. KGAA (DE) 2015-11-03 US disclosed
US-9161898-B2 Compositions for colouring keratin fibres HENKEL AG & CO. KGAA (DE) 2015-10-20 US disclosed
US-6461390-B1 Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same WELLA AKTIENGESELLSCHAFT (DE) 2002-10-08 US disclosed
US-6361571-B1 USING TAUTOMERIC NONOXIDATIVE DYES AND POLYMETHINE DYES WELLA AKTIENGESELLSCHAFT (DE) 2002-03-26 US disclosed
US-6231622-B1 MIXTURES; BLUE COLOR WELLA AKTIENGESELLSCHAFT (DE) 2001-05-15 US disclosed
US-6171347-B1 REMOVAL OF HAIR COLOR TO BE WORN FOR ONLY A SHORT PERIOD OF TIME UNDER MILD, GENTLE CONDITIONS BY USING A COMBINATION OF A SUITABLE REDUCTONE, SUCH AS ASCORBIC ACID, AND/OR A THIOL AND/OR A SULFITE WELLA AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
US-6146429-A DEVELOPER, COUPLER, BEESWAX AND PROTEIN HYDROLYZATES OR AMINO ACIDS WELLA AKTIENGESELLSCHAFT (DE) 2000-11-14 US disclosed
US-6106579-A MIXTURE OF OXOCARBOXYLIC ACID AND REDUCING AGENT WELLA AKTIENGESELLSCHAFT (DE) 2000-08-22 US disclosed
US-5865855-A COUPLING TWO PYRAZOLE COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 1999-02-02 US disclosed
EP-0229191-B1 FLY-ATTRACTIVE COMPOSITION EARTH CHEMICAL CO., LTD. (JP) 1993-06-02 EP disclosed
US-4855133-A Composition for attracting flies EARTH CHEMICAL COMPANY, LIMITED (JP) 1989-08-08 US disclosed
EP-0229191-A1 FLY-ATTRACTIVE COMPOSITION EARTH CHEMICAL CO., LTD. (JP) 1987-07-22 EP disclosed